Douglas J Goetz Selected Research

phenyl methimazole

1/2018	Phenylmethimazole abrogates diet-induced inflammation, glucose intolerance and NAFLD.
5/2017	Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells.
9/2010	Phenyl methimazole suppresses dextran sulfate sodium-induced murine colitis.
6/2009	Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration.
5/2005	Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Douglas J Goetz Research Topics

Disease

7	Inflammation (Inflammations) 12/2019 - 12/2003
5	Neoplasms (Cancer) 12/2019 - 12/2003
4	Neoplasm Metastasis (Metastasis) 11/2019 - 01/2012
3	Atherosclerosis 04/2014 - 10/2008
2	Cytokine Release Syndrome 01/2022 - 09/2020
2	Arthritis (Polyarthritis) 12/2019 - 12/2003
2	Circulating Neoplastic Cells 01/2017 - 01/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 10/2012 - 06/2009
2	Colitis 09/2010 - 05/2005
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2005 - 12/2003
2	Wounds and Injuries (Trauma) 12/2003 - 07/2002
1	COVID-19 01/2022
1	Myeloid Leukemia (Leukemia, Myelocytic) 12/2020
1	Sepsis (Septicemia) 09/2020
1	Disease Progression 04/2020
1	Bipolar Disorder (Manic Depressive Psychosis) 12/2019
1	Asthma (Bronchial Asthma) 12/2019
1	Carcinogenesis 12/2018
1	Insulin Resistance 01/2018
1	Obesity 01/2018
1	Glucose Intolerance 01/2018
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Triple Negative Breast Neoplasms 05/2017
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2015
1	Atherosclerotic Plaque (Atheroma) 04/2014
1	Ulcerative Colitis 09/2010
1	Melanoma (Melanoma, Malignant) 06/2009
1	Thyroiditis 05/2005
1	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 05/2005
1	Virus Diseases (Viral Diseases) 05/2005
1	Infections 05/2005
1	Graves Disease (Basedow Disease) 08/2004
1	Autoimmune Diseases (Autoimmune Disease) 08/2004
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2003

Drug/Important Bio-Agent (IBA)

8	LigandsIBA 11/2019 - 12/2003
6	CytokinesIBA 01/2022 - 12/2003
5	phenyl methimazoleIBA 01/2018 - 05/2005
5	E-SelectinIBA 01/2015 - 12/2003
4	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 03/2015 - 12/2003
3	Glycogen Synthase Kinase 3IBA 01/2022 - 12/2019
3	P-SelectinIBA 05/2005 - 07/2002
2	ChemokinesIBA 01/2022 - 09/2010
2	Toll-Like Receptor 4IBA 09/2020 - 01/2018
2	SelectinsIBA 11/2019 - 01/2012
2	Proteins (Proteins, Gene)FDA Link 04/2014 - 05/2005
2	Toll-Like Receptor 3IBA 06/2009 - 05/2005
2	Pharmaceutical PreparationsIBA 05/2005 - 12/2003
1	SARS-CoV-2 spike proteinIBA 01/2022
1	Interferon-gamma (Interferon, gamma)IBA 12/2020
1	LipopolysaccharidesIBA 09/2020
1	Phenobarbital (Luminal)FDA Link 04/2020
1	Triglycerides (Triacylglycerol)IBA 01/2018
1	Nonesterified Fatty Acids (NEFA)IBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	ThiazolesIBA 05/2017
1	Interleukin-6 (Interleukin 6)IBA 05/2017
1	L-SelectinIBA 01/2017
1	Protein Isoforms (Isoforms)IBA 01/2015
1	Sialyl Lewis X AntigenIBA 10/2012
1	DNA (Deoxyribonucleic Acid)IBA 10/2012
1	oxidized low density lipoproteinIBA 01/2012
1	Dextran SulfateIBA 09/2010
1	Drug CarriersIBA 10/2008
1	Apolipoproteins E (ApoE)IBA 10/2008
1	Dexamethasone (Maxidex)FDA LinkGeneric 05/2005
1	Ethylene Glycol (Monoethylene Glycol)IBA 05/2005
1	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 05/2005
1	Protein Kinases (Protein Kinase)IBA 05/2005
1	poly(lactide) (polylactic acid)IBA 05/2005
1	Methimazole (Thiamazole)FDA LinkGeneric 08/2004
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2004
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 12/2003
1	Peptides (Polypeptides)IBA 07/2002

Therapy/Procedure

2	Therapeutics 01/2022 - 09/2020
2	Microspheres (Microsphere) 12/2018 - 05/2005
1	Carotid Endarterectomy 04/2014